Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia Function

Elevated Src kinase activity is linked to the progression of solid tumors, including head and neck squamous cell carcinoma (HNSCC). Src regulates HNSCC proliferation and tumor invasion, with the Src-targeted small molecule inhibitor saracatinib displaying potent anti-invasive effects in preclinical...

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Xehetasun bibliografikoak
Egile Nagusiak: Ammer, Amanda Gatesman, Kelley, Laura C., Hayes, Karen E., Evans, Jason V., Lopez-Skinner, Lesly Ann, Martin, Karen H., Frederick, Barbara, Rothschild, Brian L., Raben, David, Elvin, Paul, Green, Tim P., Weed, Scott A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875552/
https://ncbi.nlm.nih.gov/pubmed/20505783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/1948-5956.1000009
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