Quantitative Measurement of Invadopodia-mediated Extracellular Matrix Proteolysis in Single and Multicellular Contexts

Cellular invasion into local tissues is a process important in development and homeostasis. Malregulated invasion and subsequent cell movement is characteristic of multiple pathological processes, including inflammation, cardiovascular disease and tumor cell metastasis(1). Focalized proteolytic degr...

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Autors principals: Martin, Karen H., Hayes, Karen E., Walk, Elyse L., Ammer, Amanda Gatesman, Markwell, Steven M., Weed, Scott A.
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2012
Matèries:
Cellular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3606055/
https://ncbi.nlm.nih.gov/pubmed/22952016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/4119
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