Saracatinib Impairs Head and Neck Squamous Cell Carcinoma Invasion by Disrupting Invadopodia Function

Elevated Src kinase activity is linked to the progression of solid tumors, including head and neck squamous cell carcinoma (HNSCC). Src regulates HNSCC proliferation and tumor invasion, with the Src-targeted small molecule inhibitor saracatinib displaying potent anti-invasive effects in preclinical...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ammer, Amanda Gatesman, Kelley, Laura C., Hayes, Karen E., Evans, Jason V., Lopez-Skinner, Lesly Ann, Martin, Karen H., Frederick, Barbara, Rothschild, Brian L., Raben, David, Elvin, Paul, Green, Tim P., Weed, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875552/
https://ncbi.nlm.nih.gov/pubmed/20505783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/1948-5956.1000009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados