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Active Chromatin Marks Are Retained on X Chromosomes Lacking Gene or Repeat Silencing Despite XIST/Xist Expression in Somatic Cell Hybrids

BACKGROUND: X-chromosome inactivation occurs early in mammalian development and results in the inactive X chromosome acquiring numerous hallmarks of heterochromatin. While XIST is a key player in the inactivation process, the method of action of this ncRNA is yet to be determined. METHODOLOGY/PRINCI...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thorogood, Nancy P., Brown, Carolyn J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875404/
https://ncbi.nlm.nih.gov/pubmed/20520737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010787
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