Inducible XIST-dependent X-chromosome inactivation in human somatic cells is reversible

During embryogenesis, the XIST RNA is expressed from and localizes to one X chromosome in females and induces chromosome-wide silencing. Although many changes to inactive X heterochromatin are known, the functional relationships between different modifications are not well understood, and studies of...

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Bibliographic Details
Main Authors: Chow, Jennifer C., Hall, Lisa L., Baldry, Sarah E. L., Thorogood, Nancy P., Lawrence, Jeanne B., Brown, Carolyn J.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891207/
https://ncbi.nlm.nih.gov/pubmed/17537922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610946104
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