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Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
Aminoglycosides antibiotics negate dissociation and recycling of the bacterial ribosome’s subunits by binding to Helix 69 (H69) of 23S rRNA. The differential binding of various aminoglycosides to the chemically synthesized terminal domains of the Escherichia coli and human H69 has been characterized...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2875026/ https://ncbi.nlm.nih.gov/pubmed/20110260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1253 |
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