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Pseudouridylation of helix 69 of 23S rRNA is necessary for an effective translation termination

Escherichia coli strains with inactivated rluD genes were previously found to lack the conserved pseudouridines in helix 69 of 23S ribosomal RNA and to grow slowly. A suppressor mutant was isolated with a near normal growth rate that had changed the conserved Glu-172 codon to a Lys codon in prfB, en...

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Hlavní autoři: Ejby, Morten, Sørensen, Michael A., Pedersen, Steen
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148303/
https://ncbi.nlm.nih.gov/pubmed/18032607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706558104
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