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Mutations in Conserved Helix 69 of 23S rRNA of Thermus thermophilus That Affect Capreomycin Resistance but Not Posttranscriptional Modifications

Translocation during the elongation phase of protein synthesis involves the relative movement of the 30S and 50S ribosomal subunits. This movement is the target of tuberactinomycin antibiotics. Here, we describe the isolation and characterization of mutants of Thermus thermophilus selected for resis...

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Detalhes bibliográficos
Main Authors: Monshupanee, Tanakarn, Gregory, Steven T., Douthwaite, Stephen, Chungjatupornchai, Wipa, Dahlberg, Albert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2583624/
https://ncbi.nlm.nih.gov/pubmed/18805973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00984-08
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