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Selection of heptapeptides that bind helix 69 of bacterial 23S ribosomal RNA
Helix 69 of E. coli 23S rRNA has important roles in specific steps of translation, such as subunit association, translocation, and ribosome recycling. An M13 phage library was used to identify peptide ligands with affinity for helix 69. One selected sequence, NQVANHQ, was shown through a bead assay...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594512/ https://ncbi.nlm.nih.gov/pubmed/23375098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.12.048 |
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