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Genotoxic stress causes the accumulation of the splicing regulator Sam68 in nuclear foci of transcriptionally active chromatin

DNA-damaging agents cause a multifaceted cellular stress response. Cells set in motion either repair mechanisms or programmed cell death pathways, depending on the extent of the damage and on their ability to withstand it. The RNA-binding protein (RBP) Sam68, which is up-regulated in prostate carcin...

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Autors principals: Busà, Roberta, Geremia, Raffaele, Sette, Claudio
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875014/
https://ncbi.nlm.nih.gov/pubmed/20110258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq004
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