Novel ruthenium complexes as potential drugs for Chagas's disease: enzyme inhibition and in vitro/in vivo trypanocidal activity

BACKGROUND AND PURPOSE: The discovery of the pharmacological functions of nitric oxide has led to the development of NO donor compounds as therapeutic agents. A new generation of ruthenium NO donors, cis-[Ru(NO)(bpy)(2)L]X(n), has been developed, and our aim was to show that these complexes are able...

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Bibliografski detalji
Glavni autori: Silva, Jean Jerley Nogueira, Guedes, Paulo Marcos Matta, Zottis, Aderson, Balliano, Tatiane Luciano, Nascimento Silva, Francisco Ordelei, França Lopes, Luiz Gonzaga, Ellena, Javier, Oliva, Glaucius, Andricopulo, Adriano Defini, Franco, Douglas Wagner, Silva, João Santana
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2010
Teme:
Research Papers with Commentaries
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874849/
https://ncbi.nlm.nih.gov/pubmed/20105182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00524.x
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