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In vitro and in vivo antiproliferative and trypanocidal activities of ruthenium NO donors
BACKGROUND AND PURPOSE: Many compounds liberating NO (NO donors) have been used as therapeutic agents. Here we test two ruthenium nitrosyls, which release NO when activated by biological reducing agents, for their effects in vitro and in vivo against Trypanasoma cruzi, the agent responsible for the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1978270/ https://ncbi.nlm.nih.gov/pubmed/17603548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707363 |
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