Alterations in Skeletal Muscle Fatty Acid Handling Predisposes Middle-Aged Mice to Diet-Induced Insulin Resistance

OBJECTIVE: Although advanced age is a risk factor for type 2 diabetes, a clear understanding of the changes that occur during middle age that contribute to the development of skeletal muscle insulin resistance is currently lacking. Therefore, we sought to investigate how middle age impacts skeletal...

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Autores principales: Koonen, Debby P.Y., Sung, Miranda M.Y., Kao, Cindy K.C., Dolinsky, Vernon W., Koves, Timothy R., Ilkayeva, Olga, Jacobs, René L., Vance, Dennis E., Light, Peter E., Muoio, Deborah M., Febbraio, Maria, Dyck, Jason R.B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874697/
https://ncbi.nlm.nih.gov/pubmed/20299464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1142
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