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Regulation of NOTCH Signaling by Reciprocal Inhibition of HES1 and Deltex 1 and its Role in Osteosarcoma Invasiveness
The highly-conserved NOTCH signaling pathway plays many essential roles in the development of diverse cells, tissues and organs from Drosophila to humans, and dysregulated Notch signaling contributes to several disorders, including vascular and bone defects, as well as several cancers. Here we descr...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874642/ https://ncbi.nlm.nih.gov/pubmed/20208568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.62 |
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