Driven to Death: Inhibition of Farnesylation Increases Ras Activity in Osteosarcoma and Promotes Growth Arrest and Cell Death

Por Geryk-Hall, Mandy, Yang, Yanwen, Hughes, Dennis P.M.
Publicado em 2010

New, Tolerable γ-Secretase Inhibitor Takes Desmoid Down a Notch

Por Hughes, Dennis P.M., Kummar, Shivaani, Lazar, Alexander J.
Publicado no Clin Cancer Res (2014)

Understanding the Biology of Bone Sarcoma from Early Initiating Events through Late Events in Metastasis and Disease Progression

Por Zhu, Limin, McManus, Madonna M., Hughes, Dennis P. M.
Publicado em 2013

Bone Sarcomas in Pediatrics: Progress in Our Understanding of Tumor Biology and Implications for Therapy

Por Rivera-Valentin, Rocio K., Zhu, Limin, Hughes, Dennis P. M.
Publicado no Paediatr Drugs (2015)

A critical role of Notch signaling in osteosarcoma invasion and metastasis

Por Zhang, Pingyu, Yang, Yanwen, Zweidler-McKay, Patrick A., Hughes, Dennis P.M.
Publicado em 2008

Slow down to stay alive: HER4 protects against cellular stress and confers chemoresistance in neuroblastoma

Por Hua, Yingqi, Gorshkov, Kirill, Yang, Yanwen, Wang, Wenyi, Zhang, Nianxiang, Hughes, Dennis P.M.
Publicado em 2012

Regulation of NOTCH Signaling by Reciprocal Inhibition of HES1 and Deltex 1 and its Role in Osteosarcoma Invasiveness

Por Zhang, Pingyu, Yang, Yanwen, Nolo, Riitta, Zweidler-McKay, Patrick A, Hughes, Dennis P M
Publicado em 2010

Signaling of ERBB Receptor Tyrosine Kinases Promotes Neuroblastoma Growth in vitro and in vivo

Por Richards, Kristen N., Zweidler-McKay, Patrick A., Van Roy, Nadine, Speleman, Frank, Treviño, Jesús, Zage, Peter E., Hughes, Dennis P.M.
Publicado em 2010

UBE4B Levels Are Correlated with Clinical Outcomes in Neuroblastoma Patients and with Altered Neuroblastoma Cell Proliferation and Sensitivity to EGFR Inhibitors

Por Zage, Peter E., Sirisaengtaksin, Natalie, Liu, Yin, Gireud, Monica, Brown, Brandon S., Palla, Shana, Richards, Kristen N., Hughes, Dennis P.M., Bean, Andrew J.
Publicado em 2012

The narrow-spectrum HDAC inhibitor entinostat enhances NKG2D expression without NK cell toxicity, leading to enhanced recognition of cancer cells

Por Zhu, Shiguo, Denman, Cecele J., Cobanoglu, Zehra S., Kiany, Simin, Lau, Ching C., Gottschalk, Stephen M., Hughes, Dennis P.M., Kleinerman, Eugenie S., Lee, Dean A.
Publicado em 2013