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N348I in HIV-1 Reverse Transcriptase Decreases Susceptibility to Tenofovir and Etravirine in Combination with Other Resistance Mutations

We previously demonstrated that N348I in HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance. However, both of these inhibitors are currently infrequently used in developed countries and the impact of N348I on newer RT inhibitors, such as tenofovir and etravirine, is unknown. In...

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Bibliographische Detailangaben
Hauptverfasser: Sluis-Cremer, Nicolas, Moore, Katie, Radzio, Jessica, Sonza, Secondo, Tachedjian, Gilda
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874243/
https://ncbi.nlm.nih.gov/pubmed/20010074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e3283315697
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