A carregar...
Subunit-specific mutational analysis of residue N348 in HIV-1 reverse transcriptase
BACKGROUND: N348I in HIV-1 reverse transcriptase (RT) confers resistance to zidovudine (AZT) and nevirapine. Biochemical studies demonstrated that N348I indirectly increases AZT resistance by decreasing the frequency of secondary ribonuclease H (RNase H) cleavages that reduce the RNA/DNA duplex leng...
Na minha lista:
| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3168420/ https://ncbi.nlm.nih.gov/pubmed/21859446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-69 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|