Cytotoxic activity of a recombinant fusion protein between interleukin 4 and Pseudomonas exotoxin.

A recombinant chimeric toxin in which the cell binding domain of Pseudomonas exotoxin (PE) was replaced by murine interleukin 4 (IL-4) was produced in Escherichia coli. This chimeric protein, IL-4-PE40, was cytotoxic to murine IL-4 receptor-bearing cell lines but had little effect on human cell line...

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Detaylı Bibliyografya
Asıl Yazarlar: Ogata, M, Chaudhary, V K, FitzGerald, D J, Pastan, I
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC287421/
https://ncbi.nlm.nih.gov/pubmed/2657746
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