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Substitution of foreign protein sequences into a chimeric toxin composed of transforming growth factor alpha and Pseudomonas exotoxin.

TGF alpha-PE40 is a chimeric toxin made by replacing domain Ia of Pseudomonas exotoxin (PE) with transforming growth factor alpha (TGF alpha). We have now replaced a portion of domain Ib of PE with different polypeptides or an extra domain III of PE in transforming growth factor alpha-PE40 and maint...

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Publicat a:Mol Cell Biol
Autors principals: Debinski, W, Siegall, C B, Fitzgerald, D, Pastan, I
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1991
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369490/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1671711/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.3.1751
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