Substitution of foreign protein sequences into a chimeric toxin composed of transforming growth factor alpha and Pseudomonas exotoxin.

TGF alpha-PE40 is a chimeric toxin made by replacing domain Ia of Pseudomonas exotoxin (PE) with transforming growth factor alpha (TGF alpha). We have now replaced a portion of domain Ib of PE with different polypeptides or an extra domain III of PE in transforming growth factor alpha-PE40 and maint...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Debinski, W, Siegall, C B, Fitzgerald, D, Pastan, I
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC369490/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1671711/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.3.1751-1753.1991
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