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Evaluation of the information content of RNA structure mapping data for secondary structure prediction

Structure mapping experiments (using probes such as dimethyl sulfate [DMS], kethoxal, and T1 and V1 RNases) are used to determine the secondary structures of RNA molecules. The process is iterative, combining the results of several probes with constrained minimum free-energy calculations to produce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Quarrier, Scott, Martin, Joshua S., Davis-Neulander, Lauren, Beauregard, Arthur, Laederach, Alain
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874162/
https://ncbi.nlm.nih.gov/pubmed/20413617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1988510
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