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Structural effects of linkage disequilibrium on the transcriptome

A majority of SNPs (single nucleotide polymorphisms) map to noncoding and intergenic regions of the genome. Noncoding SNPs are often identified in genome-wide association studies (GWAS) as strongly associated with human disease. Two such disease-associated SNPs in the 5′ UTR of the human FTL (Ferrit...

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Detalhes bibliográficos
Main Authors: Martin, Joshua S., Halvorsen, Matthew, Davis-Neulander, Lauren, Ritz, Justin, Gopinath, Chetna, Beauregard, Arthur, Laederach, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261746/
https://ncbi.nlm.nih.gov/pubmed/22109839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.029900.111
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