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Deletion Mutants of VPg Reveal New Cytopathology Determinants in a Picornavirus

BACKGROUND: Success of a viral infection requires that each infected cell delivers a sufficient number of infectious particles to allow new rounds of infection. In picornaviruses, viral replication is initiated by the viral polymerase and a viral-coded protein, termed VPg, that primes RNA synthesis....

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Autores principales: Arias, Armando, Perales, Celia, Escarmís, Cristina, Domingo, Esteban
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873979/
https://ncbi.nlm.nih.gov/pubmed/20505767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010735
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