Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice

BACKGROUND: Parkinson's disease (PD) is the most common movement disorder. While neuronal deposition of α-synuclein serves as a pathological hallmark of PD and Dementia with Lewy Bodies, α-synuclein-positive protein aggregates are also present in astrocytes. The pathological consequence of astr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gu, Xing-Long, Long, Cai-Xia, Sun, Lixin, Xie, Chengsong, Lin, Xian, Cai, Huaibin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873589/
https://ncbi.nlm.nih.gov/pubmed/20409326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-3-12
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