Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice

BACKGROUND: Parkinson's disease (PD) is the most common movement disorder. While neuronal deposition of α-synuclein serves as a pathological hallmark of PD and Dementia with Lewy Bodies, α-synuclein-positive protein aggregates are also present in astrocytes. The pathological consequence of astr...

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Main Authors: Gu, Xing-Long, Long, Cai-Xia, Sun, Lixin, Xie, Chengsong, Lin, Xian, Cai, Huaibin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873589/
https://ncbi.nlm.nih.gov/pubmed/20409326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-3-12
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