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Characterization of protein tyrosine phosphatase H1 knockout mice in animal models of local and systemic inflammation
BACKGROUND: PTPH1 is a protein tyrosine phosphatase expressed in T cells but its effect on immune response is still controversial. PTPH1 dephosphorylates TCRzeta in vitro, inhibiting the downstream inflammatory signaling pathway, however no immunological phenotype has been detected in primary T cell...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873500/ https://ncbi.nlm.nih.gov/pubmed/20353590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-7-16 |
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