Knockout mice reveal a role for protein tyrosine phosphatase H1 in cognition

BACKGROUND: The present study has investigated the protein tyrosine phosphatase H1 (PTPH1) expression pattern in mouse brain and its impact on CNS functions. METHODS: We have previously described a PTPH1-KO mouse, generated by replacing the PTP catalytic and the PDZ domain with a LacZ neomycin casse...

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Autori principali: Patrignani, Claudia, Magnone, Maria Chiara, Tavano, Patrizia, Ardizzone, Michele, Muzio, Valeria, Gréco, Béatrice, Zaratin, Paola F
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531118/
https://ncbi.nlm.nih.gov/pubmed/18700002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-9081-4-36
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