Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog.

Electron paramagnetic resonance (EPR) spectroscopy was used to investigate whether (i) the free radicals produced in the "stunned" myocardium (myocardium with postischemic contractile dysfunction) are derived from O2, (ii) inhibition of radical reactions improves function, and (iii) i.v. spin traps...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bolli, R, Jeroudi, M O, Patel, B S, DuBose, C M, Lai, E K, Roberts, R, McCay, P B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287338/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543984/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4695
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