Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog.

Electron paramagnetic resonance (EPR) spectroscopy was used to investigate whether (i) the free radicals produced in the "stunned" myocardium (myocardium with postischemic contractile dysfunction) are derived from O2, (ii) inhibition of radical reactions improves function, and (iii) i.v. spin traps...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Bolli, R, Jeroudi, M O, Patel, B S, DuBose, C M, Lai, E K, Roberts, R, McCay, P B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287338/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543984/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4695
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