Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog.

Electron paramagnetic resonance (EPR) spectroscopy was used to investigate whether (i) the free radicals produced in the "stunned" myocardium (myocardium with postischemic contractile dysfunction) are derived from O2, (ii) inhibition of radical reactions improves function, and (iii) i.v. spin traps...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Bolli, R, Jeroudi, M O, Patel, B S, DuBose, C M, Lai, E K, Roberts, R, McCay, P B
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1989
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287338/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543984/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4695
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