Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog.
Electron paramagnetic resonance (EPR) spectroscopy was used to investigate whether (i) the free radicals produced in the "stunned" myocardium (myocardium with postischemic contractile dysfunction) are derived from O2, (ii) inhibition of radical reactions improves function, and (iii) i.v. spin traps...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
|---|---|
| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1989
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287338/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543984/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4695 |
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