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Determination of multi-component protein structures in solution using global orientation and shape restraints
Determining architectures of multi-component proteins or protein complexes in solution is a challenging problem. Here we report a methodology that simultaneously uses residual dipolar couplings (RDC) and the small-angle X-ray scattering (SAXS) restraints to mutually orient subunits and define the gl...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873192/ https://ncbi.nlm.nih.gov/pubmed/19722627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja902528f |
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