Determination of multi-component protein structures in solution using global orientation and shape restraints

Determining architectures of multi-component proteins or protein complexes in solution is a challenging problem. Here we report a methodology that simultaneously uses residual dipolar couplings (RDC) and the small-angle X-ray scattering (SAXS) restraints to mutually orient subunits and define the gl...

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Detalhes bibliográficos
Main Authors: Wang, Jinbu, Zuo, Xiaobing, Yu, Ping, Byeon, In-Ja L., Jung, Jinwon, Wang, Xiaoxia, Dyba, Marzena, Seifert, Soenke, Schwieters, Charles D., Qin, Jun, Gronenborn, Angela M., Wang, Yun-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873192/
https://ncbi.nlm.nih.gov/pubmed/19722627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja902528f
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