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Direct Use of (15)N Relaxation Rates as Experimental Restraints on Molecular Shape and Orientation for Docking of Protein-Protein Complexes

(15)N relaxation rates contain information on overall molecular shape and size, as well as residue specific orientations of N-H bond vectors relative to the axes of the diffusion tensor. Here we describe a pseudopotential E(relax) that permits direct use of (15)N relaxation rates, in the form of R(2...

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Detalhes bibliográficos
Main Authors: Ryabov, Yaroslav, Clore, G. Marius, Schwieters, Charles D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872242/
https://ncbi.nlm.nih.gov/pubmed/20392103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja101842n
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