A Method for Helical RNA Global Structure Determination in Solution Using Small Angle X-ray Scattering and NMR Measurements

We report a “top-down” method that uses mainly duplexes' global orientations and overall molecular dimension and shape restraints, which were extracted from experimental NMR and small angle X-ray scattering (SAXS) data respectively, to determine global architectures of RNA molecules consisting...

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Detalhes bibliográficos
Main Authors: Wang, Jinbu, Zuo, Xiaobing, Yu, Ping, Xu, Huan, Starich, Mary R., Tiede, David M., Shapiro, Bruce A., Schwieters, Charles D., Wang, Yun-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2760655/
https://ncbi.nlm.nih.gov/pubmed/19666030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.001
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