Extended structures in RNA folding intermediates are due to non-native interactions rather than electrostatic repulsion

RNA folding occurs via a series of transitions between metastable intermediate states for Mg(2+) concentrations below those needed to fold the native structure. In general, these folding intermediates are considerably less compact than their respective native states. Our previous work demonstrates t...

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Main Authors: Baird, Nathan J., Gong, Haipeng, Zaheer, Syed S., Freed, Karl F., Pan, Tao, Sosnick, Tobin R.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873146/
https://ncbi.nlm.nih.gov/pubmed/20188108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.02.025
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