The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis

Epithelial organs are made of tubes and cavities lined by a monolayer of polarized cells that enclose the central lumen. Lumen formation is a crucial step in the formation of epithelial organs. The Rho guanosine triphosphatase (GTPase) Cdc42, which is a master regulator of cell polarity, regulates t...

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Autors principals: Rodriguez-Fraticelli, Alejo E., Vergarajauregui, Silvia, Eastburn, Dennis J., Datta, Anirban, Alonso, Miguel A., Mostov, Keith, Martín-Belmonte, Fernando
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2010
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872911/
https://ncbi.nlm.nih.gov/pubmed/20479469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201002047
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