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Role of Numb in Dendritic Spine Development with a Cdc42 GEF Intersectin and EphB2
Numb has been implicated in cortical neurogenesis during nervous system development, as a result of its asymmetric partitioning and antagonizing Notch signaling. Recent studies have revealed that Numb functions in clathrin-dependent endocytosis by binding to the AP-2 complex. Numb is also expressed...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Cell Biology
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1382316/ https://ncbi.nlm.nih.gov/pubmed/16394100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-07-0700 |
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