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Cell Polarity Dynamics Controls the Mechanism of Lumen Formation in Epithelial Morphogenesis

Many organs consist of tubes or spheres of epithelial cells enclosing a central lumen. How the space of this lumen is generated is a key question in morphogenesis. Two predominant mechanisms of de novo lumen formation have been observed: hollowing and cavitation. In hollowing the lumen is formed by...

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Main Authors: Martín-Belmonte, Fernando, Yu, Wei, Rodríguez-Fraticelli, Alejo E, Ewald, Andrew, Werb, Zena, Alonso, Miguel A, Mostov, Keith
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2405957/
https://ncbi.nlm.nih.gov/pubmed/18394894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.02.076
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