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Different modes of TRAF3 ubiquitination selectively activate type I interferon and proinflammatory cytokine expression

Balanced production of type I interferons (IFN) and proinflammatory cytokines upon engagement of Toll-like receptors (TLRs), which signal via adaptors containing a Toll-IL-1-Receptor (TIR) domain, such as MyD88 and TRIF, has been proposed to control the pathogenesis of autoimmune disease and tumor r...

詳細記述

保存先:
書誌詳細
主要な著者: Tseng, Ping-Hui, Matsuzawa, Atsushi, Zhang, Weizhou, Mino, Takashi, Vignali, Dario A. A., Karin, Michael
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872790/
https://ncbi.nlm.nih.gov/pubmed/19898473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1819
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