Interferon regulatory factor 4 negatively regulates the production of proinflammatory cytokines by macrophages in response to LPS

A member of the IFN regulatory factor (IRF) family of transcription factors, IRF-4 is expressed in lymphocytes and macrophage/dendritic cells. Studies using IRF-4-deficient mice have revealed the critical roles of IRF-4 in lymphocyte responses. However, the role of IRF-4 in innate immune responses i...

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Hlavní autoři: Honma, Kiri, Udono, Heiichiro, Kohno, Tomoko, Yamamoto, Kazuo, Ogawa, Asako, Takemori, Toshitada, Kumatori, Atsushi, Suzuki, Shoichi, Matsuyama, Toshifumi, Yui, Katsuyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276050/
https://ncbi.nlm.nih.gov/pubmed/16243976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504226102
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