Interferon regulatory factor 4 differentially regulates the production of Th2 cytokines in naïve vs. effector/memory CD4(+) T cells

Interferon regulatory factor (IRF) 4 is a member of the IRF family of transcription factors and plays critical roles in the development of CD4(+) T cells into Th2 and Th17 cells. Using the infection model of Nippostrongyrus brasiliensis, we have confirmed the critical roles of IRF-4 in Th2 developme...

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Detalles Bibliográficos
Main Authors: Honma, Kiri, Kimura, Daisuke, Tominaga, Norio, Miyakoda, Mana, Matsuyama, Toshifumi, Yui, Katsuyuki
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2572975/
https://ncbi.nlm.nih.gov/pubmed/18836070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803171105
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