Metformin Promotes the Protection of Mice Infected With Plasmodium yoelii Independently of γδ T Cell Expansion

Adaptive immune responses are critical for protection against infection with Plasmodium parasites. The metabolic state dramatically changes in T cells during activation and the memory phase. Recent findings suggest that metformin, a medication for treating type-II diabetes, enhances T-cell immune re...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Miyakoda, Mana, Bayarsaikhan, Ganchimeg, Kimura, Daisuke, Akbari, Masoud, Udono, Heiichiro, Yui, Katsuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6300485/
https://ncbi.nlm.nih.gov/pubmed/30619302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02942
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