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Differential methylation persists at the mouse Rasgrf1 DMR in tissues displaying monoallelic and biallelic expression

A subset of mammalian genes exhibits genomic imprinting, whereby one parental allele is preferentially expressed. Differential DNA methylation at imprinted loci serves both to mark the parental origin of the alleles and to regulate their expression. In mouse, the imprinted gene Rasgrf1 is associated...

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Библиографические подробности
Главные авторы: Dockery, Lauren, Gerfen, Jennifer, Harview, Christina, Rahn-Lee, Charlotte, Horton, Rachel, Park, Yaena, Davis, Tamara L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872782/
https://ncbi.nlm.nih.gov/pubmed/19502804
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