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The calcium-permeable non-selective cation channel TRPM2 is modulated by cellular acidification
TRPM2 is a calcium-permeable non-selective cation channel expressed in the plasma membrane and in lysosomes that is critically involved in aggravating reactive oxygen species (ROS)-induced inflammatory processes and has been implicated in cell death. TRPM2 is gated by ADP-ribose (ADPR) and modulated...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872729/ https://ncbi.nlm.nih.gov/pubmed/20194125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.187476 |
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