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Regulation of TRPM2 by Extra- and Intracellular Calcium

TRPM2 is a calcium-permeable nonselective cation channel that is opened by the binding of ADP-ribose (ADPR) to a C-terminal nudix domain. Channel activity is further regulated by several cytosolic factors, including cyclic ADPR (cADPR), nicotinamide adenine dinucleotide phosphate (NAADP), Ca(2+) and...

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Detalhes bibliográficos
Main Authors: Starkus, John, Beck, Andreas, Fleig, Andrea, Penner, Reinhold
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151648/
https://ncbi.nlm.nih.gov/pubmed/17893195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709836
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