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Lipopolysaccharide-induced down-regulation of Ca(2+) release-activated Ca(2+) currents (I(CRAC)) but not Ca(2+)-activated TRPM4-like currents (I(CAN)) in cultured mouse microglial cells
Microglia are the main immunocompetent cells of the mammalian central nervous system (CNS). Activation of cultured microglial cells and subsequent release of nitric oxide and cytokines critically depends on intracellular calcium levels. Since microglia undergo dramatic morphological, biochemical and...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375604/ https://ncbi.nlm.nih.gov/pubmed/17991695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.145151 |
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