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Lipopolysaccharide-induced down-regulation of Ca(2+) release-activated Ca(2+) currents (I(CRAC)) but not Ca(2+)-activated TRPM4-like currents (I(CAN)) in cultured mouse microglial cells
Microglia are the main immunocompetent cells of the mammalian central nervous system (CNS). Activation of cultured microglial cells and subsequent release of nitric oxide and cytokines critically depends on intracellular calcium levels. Since microglia undergo dramatic morphological, biochemical and...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375604/ https://ncbi.nlm.nih.gov/pubmed/17991695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.145151 |
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