Evidence that tricyclic small molecules may possess Toll-like receptor and MD-2 activity

Opioids have been discovered to have Toll-like receptor (TLR) activity, beyond actions at classical opioid receptors. This raises the question whether other pharmacotherapies for pain control may also possess TLR activity, contributing to or opposing their clinical effects. We document that tricycli...

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Detaylı Bibliyografya
Asıl Yazarlar: Hutchinson, Mark R., Loram, Lisa C., Zhang, Yingning, Shridhar, Mitesh, Rezvani, Niloofar, Berkelhammer, Debra, Phipps, Simon, Foster, Paul S., Landgraf, Kyle, Falke, Joseph J., Rice, Kenner C., Maier, Steven F., Yin, Hang, Watkins, Linda R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872682/
https://ncbi.nlm.nih.gov/pubmed/20381591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.03.067
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