IL-4Rα-Independent Expression of Mannose Receptor and Ym1 by Macrophages Depends on their IL-10 Responsiveness

IL-4Rα-dependent responses are essential for granuloma formation and host survival during acute schistosomiasis. Previously, we demonstrated that mice deficient for macrophage-specific IL-4Rα (LysM(cre)Il4ra(−/lox)) developed increased hepatotoxicity and gut inflammation; whereas inflammation was re...

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Autors principals: Dewals, Benjamin G., Marillier, Reece G., Hoving, Jennifer C., Leeto, Mosiuoa, Schwegmann, Anita, Brombacher, Frank
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872644/
https://ncbi.nlm.nih.gov/pubmed/20502521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000689
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